75,329 research outputs found
Strong polygamy of quantum correlations in multi-party quantum systems
We propose a new type of polygamy inequality for multi-party quantum
entanglement. We first consider the possible amount of bipartite entanglement
distributed between a fixed party and any subset of the rest parties in a
multi-party quantum system. By using the summation of these distributed
entanglements, we provide an upper bound of the distributed entanglement
between a party and the rest in multi-party quantum systems. We then show that
this upper bound also plays as a lower bound of the usual polygamy inequality,
therefore the strong polygamy of multi-party quantum entanglement. For the case
of multi-party pure states, we further show that the strong polygamy of
entanglement implies the strong polygamy of quantum discord.Comment: 5 page
SAR Studies on the Inhibitors for the Treatment of Inflammatory Diseases
School of Molecular Sciences(Chemistry)Inflammation is defensive host response that occurs from infection and injury and the inflammatory process is the pivotal physiological response of our body and essential part of the human physiology. Due to the mechanistic relationship between chronic diseases and inflammation, a better understanding for the molecular mechanism of chronic inflammation could attenuate cellular inflammation pathways. Under inflammatory pathways, the impetus of proinflammatory mediators usually caused by the increased expression of transcriptional factors which is also a potential targets in the development of novel and effective anti-inflammatory therapeutics. Among others, we are interested in the Nuclear Factor Kappa-B (NF-??B) which is reported as a major mediator that regulates inflammatory gene expression and also decrease the prevalence of inflammation responses. To suppress the inflammatory activity, inhibitors that could selectively target this protein are needed. We therefore, chose the natural product cerulenin which has been studied widely because of its antifungal and antibacterial properties, for designing inhibitors. In light of the interesting inhibitory properties displayed by cerulenin for fatty acid synthase (FASN), we were keen to explore the possible binding mode of this natural product with a view to design various derivatives that would be amicable to synthetic manipulation in order to enable SAR studies. Potent analogues of cerulenin, with various chain lengths and substitutions, are synthesized and evaluated for their ability to inhibit NF-??B enhanceosome. Taken together, by identifying target protein with constructed inhibitors derived from cerulenin might give revolutionary effect on discovering new therapeutic agents.ope
t-tbar Pair production cross section measurement at the LHC
Measurement of pair production cross sections with an integrated
luminosity of around 1 fb at = 7 TeV obtained with the ATLAS
and CMS detectors are reported. The inclusive cross sections in dilepton (ee,
, and ), lepton+jets (e, ) and all hadronic decay
modes are measured. In addition to inclusive cross section measurement, the
study of jet multiplicity with additional jets are also presented, which is
important to constrain the initial state radiation. Measurement of the charge
asymmetry at the LHC is also presented. All measurements are compatible with
Standard Model predictions.Comment: Presented at the 2011 Hadron Collider Physics symposium (HCP-2011),
Paris, France, November 14-18 2011, 5 pages, 7 figure
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